Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells

Haematopoietic stem cells (HSCs) are maintained by bone marrow (BM) niches in vivo(1,2), but the ability of niche cells to maintain HSCs ex vivo is markedly diminished. Expression of niche factors by Nestin-GFP(+) mesenchymal-derived stromal cells (MSCs) is downregulated upon culture, suggesting tha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Nakahara, Fumio, Borger, Daniel K., Wei, Qiaozhi, Pinho, Sandra, Maryanovich, Maria, Zahalka, Ali H., Suzuki, Masako, Cruz, Cristian D., Wang, Zichen, Xu, Chunliang, Boulais, Philip E., Ma'ayan, Avi, Greally, John M., Frenette, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499646/
https://ncbi.nlm.nih.gov/pubmed/30988422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0308-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados