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Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus

NsaS is one of four intramembrane histidine kinases (HKs) in Staphylococcus aureus that mediate the pathogen’s response to membrane active antimicrobials and human innate immunity. We describe the first integrative structural study of NsaS using a combination of solution state NMR spectroscopy, chem...

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Bhate, Manasi P., Lemmin, Thomas, Kuenze, Georg, Mensa, Bruk, Ganguly, Soumya, Peters, Jason M., Schmidt, Nathan, Pelton, Jeffrey G., Gross, Carol A., Meiler, Jens, DeGrado, William F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499544/
https://ncbi.nlm.nih.gov/pubmed/29771498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09670
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