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Age and stage dependency of estrogen receptor expression by lymphocyte precursors

Sex steroids negatively regulate B lymphopoiesis in adult mice. Paradoxically, lymphocytes arise during fetal life, when estrogen levels are high and maternal lymphopoiesis is suppressed. Here we demonstrate that embryonic B lymphopoiesis was unaffected by estrogen, but sensitive to glucocorticoids....

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Détails bibliographiques
Auteurs principaux: Igarashi, Hideya, Kouro, Taku, Yokota, Takafumi, Comp, Phillip C., Kincade, Paul W.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC64995/
https://ncbi.nlm.nih.gov/pubmed/11752459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.011513098
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