SFRP1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis

It has long been known that lymphopoiesis is transiently suppressed during pregnancy, which can be experimentally simulated by estrogen treatment. We now confirm with Rag1/GFP reporter mice that early lymphoid progenitors in the lineage marker(-) c-kit(Hi) Sca1(+), hematopoietic stem cells (HSC)-enr...

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Autori principali: Yokota, Takafumi, Oritani, Kenji, Garrett, Karla P., Kouro, Taku, Nishida, Makoto, Takahashi, Isao, Ichii, Michiko, Satoh, Yusuke, Kincade, Paul W., Kanakura, Yuzuru
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735054/
https://ncbi.nlm.nih.gov/pubmed/18941195
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