Metabolomics of Neonatal Blood Spots Reveal Distinct Phenotypes of Pediatric Acute Lymphoblastic Leukemia and Potential Effects of Early-life Nutrition

Early-life exposures are believed to influence the incidence of pediatric acute lymphoblastic leukemia (ALL). Archived neonatal blood spots (NBS), collected within the first days of life, offer a means to investigate small molecules that reflect early-life exposures. Using untargeted metabolomics, w...

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Veröffentlicht in:Cancer Lett
Hauptverfasser: Petrick, Lauren M., Schiffman, Courtney, Edmands, William M.B., Yano, Yukiko, Perttula, Kelsi, Whitehead, Todd, Metayer, Catherine, Wheelock, Craig E., Arora, Manish, Grigoryan, Hasmik, Carlsson, Henrik, Dudoit, Sandrine, Rappaport, Stephen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499387/
https://ncbi.nlm.nih.gov/pubmed/30904619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.03.007
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