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Transgenic Exosomes for Thymus Regeneration
During senescence, Wnt4 expression is down-regulated (unlike their Frizzled receptors), while PPARgamma expression increases in the thymus. Together, these changes allow for thymic degeneration to occur, observed as adipose involution. However, when restored, Wnt4 can efficiently counteract PPARgamm...
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| Publicado en: | Front Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6499203/ https://ncbi.nlm.nih.gov/pubmed/31110503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00862 |
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