Computational Studies on the Potency and Selectivity of PUGNAc Derivatives Against GH3, GH20, and GH84 β-N-acetyl-D-hexosaminidases

β-N-acetyl-D-hexosaminidases have attracted significant attention due to their crucial role in diverse physiological functions including antibacterial synergists, pathogen defense, virus infection, lysosomal storage, and protein glycosylation. In particular, the GH3 β-N-acetyl-D-hexosaminidase of V....

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Dong, Lili, Shen, Shengqiang, Xu, Yefei, Wang, Leng, Feng, Ruirui, Zhang, Jianjun, Lu, Huizhe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499197/
https://ncbi.nlm.nih.gov/pubmed/31111026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00235
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