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scruff: an R/Bioconductor package for preprocessing single-cell RNA-sequencing data

BACKGROUND: Single-cell RNA sequencing (scRNA-seq) enables the high-throughput quantification of transcriptional profiles in single cells. In contrast to bulk RNA-seq, additional preprocessing steps such as cell barcode identification or unique molecular identifier (UMI) deconvolution are necessary...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Main Authors: Wang, Zhe, Hu, Junming, Johnson, W. Evan, Campbell, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498700/
https://ncbi.nlm.nih.gov/pubmed/31046658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2797-2
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