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scPipe: A flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data

Single-cell RNA sequencing (scRNA-seq) technology allows researchers to profile the transcriptomes of thousands of cells simultaneously. Protocols that incorporate both designed and random barcodes have greatly increased the throughput of scRNA-seq, but give rise to a more complex data structure. Th...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Autores principales: Tian, Luyi, Su, Shian, Dong, Xueyi, Amann-Zalcenstein, Daniela, Biben, Christine, Seidi, Azadeh, Hilton, Douglas J., Naik, Shalin H., Ritchie, Matthew E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105007/
https://ncbi.nlm.nih.gov/pubmed/30096152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006361
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