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DNA-PKcs is critical for telomere capping

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is critical for DNA repair via the nonhomologous end joining pathway. Previously, it was reported that bone marrow cells and spontaneously transformed fibroblasts from SCID (severe combined immunodeficiency) mice have defects in telomere...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gilley, David, Tanaka, Hiromi, Hande, M. Prakash, Kurimasa, Akihiro, Li, Gloria C., Oshimura, Mitsuo, Chen, David J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2001
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11742099/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261574698
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