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DNA-PKcs is critical for telomere capping

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is critical for DNA repair via the nonhomologous end joining pathway. Previously, it was reported that bone marrow cells and spontaneously transformed fibroblasts from SCID (severe combined immunodeficiency) mice have defects in telomere...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gilley, David, Tanaka, Hiromi, Hande, M. Prakash, Kurimasa, Akihiro, Li, Gloria C., Oshimura, Mitsuo, Chen, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC64987/
https://ncbi.nlm.nih.gov/pubmed/11742099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261574698
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