Monoclonal antibody against N2 neuraminidase of cold adapted A/Leningrad/134/17/57 (H2N2) enables efficient generation of live attenuated influenza vaccines

Cold adapted influenza virus A/Leningrad/134/17/57 (H2N2) is a reliable master donor virus (Len/17-MDV) for preparing live attenuated influenza vaccines (LAIV). LAIVs are 6:2 reasortants that contain 6 segments of Len/17-MDV and the hemagglutinin (HA) and neuraminidase (NA) of contemporary circulati...

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Publicat a:Virology
Autors principals: Shcherbik, Svetlana, Carney, Paul, Pearce, Nicholas, Stevens, James, Dugan, Vivien G., Wentworth, David E., Bousse, Tatiana
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498426/
https://ncbi.nlm.nih.gov/pubmed/30014859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.07.005
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