Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions

Gut mucosal healing (MH) is considered a key therapeutic target and prognostic parameter in the management of inflammatory bowel disease (IBD). The dipotassium glycyrrhizate (DPG), a salt of the glycoconjugated triterpene glycyrrhizin, has been shown to inhibit the High Mobility Group Box 1 (HMGB1)...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Stronati, Laura, Palone, Francesca, Negroni, Anna, Colantoni, Eleonora, Mancuso, Anna Barbara, Cucchiara, Salvatore, Cesi, Vincenzo, Isoldi, Sara, Vitali, Roberta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498413/
https://ncbi.nlm.nih.gov/pubmed/31105713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00939
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