Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice

BACKGROUND: High mobility group box-1 (HMGB1) is a DNA-binding protein that is released from injured cells during inflammation. Advances in targeting HMGB1 represent a major challenge to improve the treatment of acute/chronic inflammation. AIM: This study is aimed at verifying whether the inhibition...

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Main Authors: Vitali, Roberta, Palone, Francesca, Cucchiara, Salvatore, Negroni, Anna, Cavone, Leonardo, Costanzo, Manuela, Aloi, Marina, Dilillo, Anna, Stronati, Laura
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686690/
https://ncbi.nlm.nih.gov/pubmed/23840500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066527
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