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Exploiting Prophage-Mediated Lysis for Biotherapeutic Release by Lactobacillus reuteri

Lactobacillus reuteri has the potential to be developed as a microbial therapeutic delivery platform because of an established safety profile, health-promoting properties, and available genome editing tools. Here, we show that L. reuteri VPL1014 exhibits a low mutation rate compared to other Gram-po...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Alexander, Laura M., Oh, Jee-Hwan, Stapleton, Donald S., Schueler, Kathryn L., Keller, Mark P., Attie, Alan D., van Pijkeren, Jan-Peter
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498169/
https://ncbi.nlm.nih.gov/pubmed/30683744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02335-18
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