UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation

Mitochondria are major sites of energy metabolism that influence numerous cellular events, including immunity and cancer development. Previously, we reported that the mitochondrion-specific antioxidant enzyme, manganese-containing superoxide dismutase (MnSOD), has dual roles in early- and late-carci...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Dhar, Sanjit K., Batinic-Haberle, Ines, St. Clair, Daret K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497943/
https://ncbi.nlm.nih.gov/pubmed/30858178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006595
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