Restrained Dendritic Growth of Adult-Born Granule Cells Innervated by Transplanted Fetal GABAergic Interneurons in Mice with Temporal Lobe Epilepsy

The dentate gyrus (DG) is a region of the adult rodent brain that undergoes continuous neurogenesis. Seizures and loss or dysfunction of GABAergic synapses onto adult-born dentate granule cells (GCs) alter their dendritic growth and migration, resulting in dysmorphic and hyperexcitable GCs. Addition...

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Veröffentlicht in:eNeuro
Hauptverfasser: Gupta, Jyoti, Bromwich, Mark, Radell, Jake, Arshad, Muhammad N., Gonzalez, Selena, Luikart, Bryan W., Aaron, Gloster B., Naegele, Janice R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2019
Schlagworte:
New Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497906/
https://ncbi.nlm.nih.gov/pubmed/31043461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0110-18.2019
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