Differentiation and Functional Incorporation of Embryonic Stem Cell-Derived GABAergic Interneurons in the Dentate Gyrus of Mice with Temporal Lobe Epilepsy

Cell therapies for neurological disorders require an extensive knowledge of disease-associated neuropathology and procedures for generating neurons for transplantation. In many patients with severe acquired temporal lobe epilepsy (TLE), the dentate gyrus exhibits sclerosis and GABAergic interneuron...

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Autors principals: Maisano, Xu, Litvina, Elizabeth, Tagliatela, Stephanie, Aaron, Gloster B., Grabel, Laura B., Naegele, Janice R.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548598/
https://ncbi.nlm.nih.gov/pubmed/22219269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2683-11.2012
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