Untargeted metabolomics reveals N, N, N-trimethyl-L-alanyl-L-proline betaine (TMAP) as a novel biomarker of kidney function

The diagnosis and prognosis of chronic kidney disease (CKD) currently relies on very few circulating small molecules, which can vary by factors unrelated to kidney function. In end-stage renal disease (ESRD), these same small molecules are used to determine dialysis dose and dialytic clearance. Ther...

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Vydáno v:Sci Rep
Hlavní autoři: Velenosi, Thomas J., Thomson, Benjamin K. A., Tonial, Nicholas C., RaoPeters, Adrien A. E., Mio, Megan A., Lajoie, Gilles A., Garg, Amit X., House, Andrew A., Urquhart, Bradley L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497643/
https://ncbi.nlm.nih.gov/pubmed/31048706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42992-3
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