Myc and loss of p53 cooperate to drive formation of choroid plexus carcinoma

Choroid plexus carcinoma (CPC) is a rare brain tumor that occurs most commonly in very young children and has a dismal prognosis despite intensive therapy. Improved outcomes for CPC patients depend on a deeper understanding of the mechanisms underlying the disease. Here we developed transgenic model...

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Publicado no:Cancer Res
Main Authors: Wang, Jun, Merino, Diana M., Light, Nicholas, Murphy, Brian L., Wang, Yong-Dong, Guo, Xiaohui, Hodges, Andrew P., Chau, Lianne Q., Liu, Kun-Wei, Dhall, Girish, Asgharzadeh, Shahab, Kiehna, Erin N., Shirey, Ryan J., Janda, Kim D., Taylor, Michael D., Malkin, David, Ellison, David W., VandenBerg, Scott R., Eberhart, Charles G., Sears, Rosalie C., Roussel, Martine F., Gilbertson, Richard J., Wechsler-Reya, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497574/
https://ncbi.nlm.nih.gov/pubmed/30885981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2565
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