Plasminogen activator inhibitor 1 (PAI1) promotes actin cytoskeleton reorganization and glycolytic metabolism in triple negative breast cancer

Migration and invasion of cancer cells constitute fundamental processes in tumor progression and metastasis. Migratory cancer cells commonly upregulate expression of plasminogen activator inhibitor 1 (PAI1), and PAI1 correlates with poor prognosis in breast cancer. However, mechanisms by which PAI1...

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Publicado en:Mol Cancer Res
Autores principales: Humphries, Brock, Buschhaus, Johanna M., Chen, Yu-Chih, Haley, Henry R., Qyli, Tonela, Chiang, Benjamin, Shen, Nathan, Rajendran, Shrila, Cutter, Alyssa, Cheng, Yu-Heng, Chen, Yu-Ting, Cong, Jason, Spinosa, Phillip C., Yoon, Euisik, Luker, Kathryn E., Luker, Gary D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497540/
https://ncbi.nlm.nih.gov/pubmed/30718260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0836
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