Plasminogen activator inhibitor 1 (PAI1) promotes actin cytoskeleton reorganization and glycolytic metabolism in triple negative breast cancer

Migration and invasion of cancer cells constitute fundamental processes in tumor progression and metastasis. Migratory cancer cells commonly upregulate expression of plasminogen activator inhibitor 1 (PAI1), and PAI1 correlates with poor prognosis in breast cancer. However, mechanisms by which PAI1...

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Publicat a:Mol Cancer Res
Autors principals: Humphries, Brock, Buschhaus, Johanna M., Chen, Yu-Chih, Haley, Henry R., Qyli, Tonela, Chiang, Benjamin, Shen, Nathan, Rajendran, Shrila, Cutter, Alyssa, Cheng, Yu-Heng, Chen, Yu-Ting, Cong, Jason, Spinosa, Phillip C., Yoon, Euisik, Luker, Kathryn E., Luker, Gary D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497540/
https://ncbi.nlm.nih.gov/pubmed/30718260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0836
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