A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

There is mounting evidence that seemingly diverse psychiatric disorders share genetic etiology, but the biological substrates mediating this overlap are not well characterized. Here, we leverage the unique iPSYCH study, a nationally representative cohort ascertained through clinical psychiatric diag...

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Udgivet i:Nat Neurosci
Main Authors: Schork, Andrew J., Won, Hyejung, Appadurai, Vivek, Nudel, Ron, Gandal, Mike, Delaneau, Olivier, Christiansen, Malene Revsbech, Hougaard, David M., Bækved-Hansen, Marie, Bybjerg-Grauholm, Jonas, Pedersen, Marianne Giørtz, Agerbo, Esben, Pedersen, Carsten Bøcker, Neale, Benjamin M., Daly, Mark J., Wray, Naomi R., Nordentoft, Merete, Mors, Ole, Børglum, Anders D., Mortensen, Preben Bo, Buil, Alfonso, Thompson, Wesley K., Geschwind, Daniel, Werge, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497521/
https://ncbi.nlm.nih.gov/pubmed/30692689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0320-0
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