A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

There is mounting evidence that seemingly diverse psychiatric disorders share genetic etiology, but the biological substrates mediating this overlap are not well characterized. Here, we leverage the unique iPSYCH study, a nationally representative cohort ascertained through clinical psychiatric diag...

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Pubblicato in:Nat Neurosci
Autori principali: Schork, Andrew J., Won, Hyejung, Appadurai, Vivek, Nudel, Ron, Gandal, Mike, Delaneau, Olivier, Christiansen, Malene Revsbech, Hougaard, David M., Bækved-Hansen, Marie, Bybjerg-Grauholm, Jonas, Pedersen, Marianne Giørtz, Agerbo, Esben, Pedersen, Carsten Bøcker, Neale, Benjamin M., Daly, Mark J., Wray, Naomi R., Nordentoft, Merete, Mors, Ole, Børglum, Anders D., Mortensen, Preben Bo, Buil, Alfonso, Thompson, Wesley K., Geschwind, Daniel, Werge, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497521/
https://ncbi.nlm.nih.gov/pubmed/30692689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0320-0
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