Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish

Glycine receptors (GlyRs) are ligand-gated chloride channels mediating inhibitory neurotransmission in the brain stem and spinal cord. They function as pentamers composed of alpha and beta subunits for which 5 genes have been identified in human (GLRA1, GLRA2, GLRA3, GLRA4, GLRB). Several in vitro s...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Samarut, Eric, Chalopin, Domitille, Riché, Raphaëlle, Allard, Marc, Liao, Meijiang, Drapeau, Pierre
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497278/
https://ncbi.nlm.nih.gov/pubmed/31048868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216159
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