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Balance of mechanical forces drives endothelial gap formation and may facilitate cancer and immune-cell extravasation

The formation of gaps in the endothelium is a crucial process underlying both cancer and immune cell extravasation, contributing to the functioning of the immune system during infection, the unfavorable development of chronic inflammation and tumor metastasis. Here, we present a stochastic-mechanica...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Escribano, Jorge, Chen, Michelle B., Moeendarbary, Emad, Cao, Xuan, Shenoy, Vivek, Garcia-Aznar, Jose Manuel, Kamm, Roger D., Spill, Fabian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497229/
https://ncbi.nlm.nih.gov/pubmed/31048903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006395
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