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Balance of mechanical forces drives endothelial gap formation and may facilitate cancer and immune-cell extravasation

The formation of gaps in the endothelium is a crucial process underlying both cancer and immune cell extravasation, contributing to the functioning of the immune system during infection, the unfavorable development of chronic inflammation and tumor metastasis. Here, we present a stochastic-mechanica...

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Publicado en:PLoS Comput Biol
Autores principales: Escribano, Jorge, Chen, Michelle B., Moeendarbary, Emad, Cao, Xuan, Shenoy, Vivek, Garcia-Aznar, Jose Manuel, Kamm, Roger D., Spill, Fabian
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497229/
https://ncbi.nlm.nih.gov/pubmed/31048903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006395
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