Circulating glioma cells exhibit stem cell-like properties

Circulating tumor cells (CTC) are known to be present in the blood of glioblastoma (GBM) patients. Here we report that GBM-derived CTC possess a cancer stem cell (CSC)-like phenotype and contribute to local tumorigenesis and recurrence by the process of self-seeding. Genetic probes showed that mouse...

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Pubblicato in:Cancer Res
Autori principali: Liu, Tianrun, Xu, Haineng, Huang, Menggui, Ma, Wenjuan, Saxena, Deeksha, Lustig, Robert A, Alonso-Basanta, Michelle, Zhang, Zhenfeng, O’Rourke, Donald M, Zhang, Lin, Gong, Yanqing, Kao, Gary D, Dorsey, Jay F, Fan, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497085/
https://ncbi.nlm.nih.gov/pubmed/30322863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0650
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