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Exposing the Nucleation Site in α-Helix Folding: A Joint Experimental and Simulation Study

One of the fundamental events in protein folding is α-helix formation, which involves sequential development of a series of helical hydrogen bonds between the backbone C=O group of residues i and the –NH group of residues i + 4. While we now know a great deal about α-helix folding dynamics, a key qu...

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Detalles Bibliográficos
Publicado en:J Phys Chem B
Main Authors: Acharyya, Arusha, Ge, Yunhui, Wu, Haifan, DeGrado, William F., Voelz, Vincent A., Gai, Feng
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497059/
https://ncbi.nlm.nih.gov/pubmed/30694671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b12220
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