Osteopontin Promotes Colorectal Cancer Cell Invasion and the Stem Cell-Like Properties through the PI3K-AKT-GSK/3β-β/Catenin Pathway

BACKGROUND: Osteopontin (OPN) is a molecule expressed in numerous cancers including colorectal cancer (CRC) that correlates disease progression. The interaction of OPN that promotes CRC cell migration, invasion, and cancer stem-like cells (CSCs) have not been elucidated. Hence, we aimed to investiga...

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Vydáno v:Med Sci Monit
Hlavní autoři: Cheng, Yuanguang, Wen, Gang, Sun, Yong, Shen, Yang, Zeng, Yongqing, Du, Ming, Zhu, Guangyu, Wang, Guanglong, Meng, Xiangling
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496974/
https://ncbi.nlm.nih.gov/pubmed/31017126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.913185
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