Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling

Cadmium has been widely used in industry and is known to be carcinogenic to humans. Although it is widely accepted that chronic exposure to cadmium increases the incidence of cancer, the mechanisms underlying cadmium-induced carcinogenesis are unclear. The main aim of this study was to investigate t...

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Main Authors: Son, Young-Ok, Wang, Lei, Poyil, Pratheeshkumar, Budhraja, Amit, Hitron, J. Andrew, Zhang, Zhuo, Lee, Jeong-Chae, Shi, Xianglin
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462234/
https://ncbi.nlm.nih.gov/pubmed/22884995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.07.028
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