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Deep Sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individuals: RYR3 deep sequencing and subclinical atherosclerosis

Carotid intima-media thickness (cIMT) is a subclinical measure of atherosclerosis with mounting evidence that higher cIMT confers an increased risk of cardiovascular disease (CVD). The ryanodine receptor 3 gene (RYR3) has previously been linked to increased cIMT; however, the causal variants have no...

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Detalhes bibliográficos
Publicado no:J Hum Genet
Main Authors: Zhi, Degui, Shendre, Aditi, Scherzer, Rebecca, Irvin, Marguerite R, Perry, Rodney T, Levy, Shawn, Arnett, Donna K, Grunfeld, Carl, Shrestha, Sadeep
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496937/
https://ncbi.nlm.nih.gov/pubmed/25500725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2014.104
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