Deep Sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individuals: RYR3 deep sequencing and subclinical atherosclerosis

Carotid intima-media thickness (cIMT) is a subclinical measure of atherosclerosis with mounting evidence that higher cIMT confers an increased risk of cardiovascular disease (CVD). The ryanodine receptor 3 gene (RYR3) has previously been linked to increased cIMT; however, the causal variants have no...

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Veröffentlicht in:J Hum Genet
Hauptverfasser: Zhi, Degui, Shendre, Aditi, Scherzer, Rebecca, Irvin, Marguerite R, Perry, Rodney T, Levy, Shawn, Arnett, Donna K, Grunfeld, Carl, Shrestha, Sadeep
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496937/
https://ncbi.nlm.nih.gov/pubmed/25500725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2014.104
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