Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony‐stimulating factor derivative Maxy‐G34 and pegfilgrastim in rats

Objectives:  This study aims to compare pharmacokinetics and pharmacodynamics of pegfilgrastim, a pharmaceutical recombinant human granulocyte colony‐stimulating factor (rhG‐CSF), with that of a newly developed reagent, Maxy‐G34. This comparison was performed using rat experiments and biomathematica...

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Publicat a:Cell Prolif
Autors principals: Scholz, M., Engel, C., Apt, D., Sankar, S. L., Goldstein, E., Loeffler, M.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496908/
https://ncbi.nlm.nih.gov/pubmed/19780759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2009.00641.x
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