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A pharmacokinetic model of filgrastim and pegfilgrastim application in normal mice and those with cyclophosphamide‐induced granulocytopaenia
Objectives: Recombinant human granulocyte colony‐stimulating factor (rhG‐CSF) is widely used as treatment for granulocytopaenia during cytotoxic chemotherapy; however, optimal scheduling of this pharmaceutical is unknown. Biomathematical models can help to pre‐select optimal application schedules b...
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| Published in: | Cell Prolif |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Publishing Ltd
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6496189/ https://ncbi.nlm.nih.gov/pubmed/19689472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2009.00638.x |
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