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The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer

Abstract.  The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This review will focus on these mechanisms, i.e. regulation of cyclin‐dependent kinases (CDK) by cyclins, CDK inhibitors and phosphorylating events. The quality checkpoints activated after DNA damage are a...

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Publicat a:Cell Prolif
Autors principals: Vermeulen, Katrien, Van Bockstaele, Dirk R., Berneman, Zwi N.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd. 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496723/
https://ncbi.nlm.nih.gov/pubmed/12814430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2003.00266.x
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