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The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer

Abstract.  The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This review will focus on these mechanisms, i.e. regulation of cyclin‐dependent kinases (CDK) by cyclins, CDK inhibitors and phosphorylating events. The quality checkpoints activated after DNA damage are a...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Vermeulen, Katrien, Van Bockstaele, Dirk R., Berneman, Zwi N.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd. 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496723/
https://ncbi.nlm.nih.gov/pubmed/12814430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2003.00266.x
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