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Stem cell factor is essential for preserving NOD/SCID reconstitution capacity of ex vivo expanded cord blood CD34(+) cells

OBJECTIVES: Stem cell factor (SCF) is essential in the haematopoietic stem cells (HSCs) niche, and is therefore used extensively in haematopoietic stem and progenitor cells (HSPCs) ex vivo expansion. However, in the literature, dose and schedule of SCF feeding varies widely. We previously proposed a...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Du, Zheng, Wang, Ziyan, Zhang, Weiwei, Cai, Haibo, Tan, Wen‐Song
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496601/
https://ncbi.nlm.nih.gov/pubmed/25899394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12186
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