No Synergistic Effect of Cotransplantation of MSC and Ex Vivo TPO-Expanded CD34(+) Cord Blood Cells on Platelet Recovery and Bone Marrow Engraftment in NOD SCID Mice

After cord blood (CB) transplantation, early platelet recovery in immune-deficient mice is obtained by expansion of CB CD34(+) cells with thrombopoietin (TPO) as single growth factor. Moreover, improvement of hematopoietic engraftment has been shown by cotransplantation of mesenchymal stem cells (MS...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Dev
Autori principali: van der Garde, Mark, Brand, Anneke, Slot, Manon C., de Graaf-Dijkstra, Alice, Zwaginga, Jaap Jan, van Hensbergen, Yvette
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2015
Soggetti:
Original Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485368/
https://ncbi.nlm.nih.gov/pubmed/25668618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0543
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