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Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells

Objectives:  Histone deacetylase (HDAC) is an important therapeutic target in cancer. Two of the main anticancer mechanisms of HDAC inhibitors are induction of terminal differentiation and inhibition of cell proliferation. To investigate the role of HDAC in maintenance of self‐renewal and cell proli...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Lee, S., Park, J‐R., Seo, M‐S., Roh, K‐H., Park, S‐B., Hwang, J‐W., Sun, B., Seo, K., Lee, Y‐S., Kang, S‐K., Jung, J‐W., Kang, K‐S.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496408/
https://ncbi.nlm.nih.gov/pubmed/19689470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2009.00633.x
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