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Structural Basis of Nuclear pre-mRNA Splicing: Lessons from Yeast
Noncoding introns are removed from nuclear precursor messenger RNA (pre-mRNA) in a two-step phosphoryl transfer reaction by the spliceosome, a dynamic multimegadalton enzyme. Cryo-electron microscopy (cryo-EM) structures of the Saccharomyces cerevisiae spliceosome were recently determined in eight k...
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| Publicado no: | Cold Spring Harb Perspect Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6496352/ https://ncbi.nlm.nih.gov/pubmed/30765413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032391 |
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