Preconditioning of umbilical cord‐derived mesenchymal stem cells by rapamycin increases cell migration and ameliorates liver ischaemia/reperfusion injury in mice via the CXCR4/CXCL12 axis

OBJECTIVES: Transfusion of umbilical cord‐derived mesenchymal stem cells (UC‐MSCs) is a novel strategy for treatment of various liver diseases. However, the therapeutic effect of UC‐MSCs is limited because only a few UC‐MSCs migrate towards the damaged regions. In this study, we observed the effects...

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Udgivet i:Cell Prolif
Main Authors: Zheng, Jun, Li, Hui, He, Liying, Huang, Yiming, Cai, Jianye, Chen, Liang, Zhou, Chaorong, Fu, Hongyuan, Lu, Tongyu, Zhang, Yingcai, Yao, Jia, Yang, Yang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496237/
https://ncbi.nlm.nih.gov/pubmed/30537044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12546
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