The role of various Bcl‐2 domains in the anti‐proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain

Abstract. Reduced cell proliferation and increased levels of cellular glutathione (GSH) are characteristic for cells that overexpress the anti‐apoptotic Bcl‐2 protein. We investigated the influence of various Bcl‐2 domains on both these characteristics. Rat CC531 colorectal cancer cells were stably...

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Vydáno v:Cell Prolif
Hlavní autoři: Hoetelmans, R. W. M., Vahrmeijer, A. L., Van Vlierberghe, R. L. P., Keijzer, R., Van De Velde, C. J. H., Mulder, G. J., Van Dierendonck, J. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Ltd 2003
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496226/
https://ncbi.nlm.nih.gov/pubmed/12558659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2003.00252.x
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