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Killing of Sarcoma Cells by Proapoptotic Bcl-X(S): Role of the BH3 Domain and Regulation by Bcl-X(L)

Kaposi's sarcoma (KS) is the most common tumor affecting AIDS patients with over 20% of these patients afflicted by this disease. Previous studies have demonstrated that KS tumor cells predominantly express the prosurvival protein Bcl-X(L) compared with Bcl-2. In the current study, we have used...

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Detalhes bibliográficos
Main Authors: Mitra, Raj S, Benedict, Mary A, Qian, Dalong, Foreman, Kimberly E, Ekhterae, Daryoush, Nickoloff, Brian J, Nuñez, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1506204/
https://ncbi.nlm.nih.gov/pubmed/11687955
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