Influence on antiproliferative activity of structural modification and conjugation of gonadotropin‐releasing hormone (GnRH) analogues

The effect of various GnRH analogues, and their conjugates on proliferation, clonogenicity and cell cycle phase distribution of MCF‐7 and Ishikawa human cancer cell lines was studied. GnRH‐III, a sea lamprey GnRH analogue reduced cell proliferation by 35% and clonogenicity by 55%. Structural modific...

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Bibliografiske detaljer
Udgivet i:Cell Prolif
Main Authors: Kálnay, A., Pályi, I., Vincze, B., Mihalik, R., Mezõ, I., Pató, J., Seprõdi, J., Lovas, S., Murphy, R.F.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Ltd 2001
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496190/
https://ncbi.nlm.nih.gov/pubmed/11063130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2000.00180.x
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