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Normal red blood cells partially decrease diepoxybutane‐induced chromosome breakage in cultured lymphocytes from Fanconi anaemia patients

Objectives:  Fanconi anaemia (FA) is a cancer‐prone chromosome instability syndrome characterized by hypersensitivity to DNA cross‐linking agents, such as diepoxybutane (DEB). Previous studies have shown that normal red blood cells (RBC) can protect cultured lymphocytes against chromosomal breaks in...

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Bibliografske podrobnosti
izdano v:Cell Prolif
Main Authors: Porto, B., Sousa, R., Malheiro, I., Gaspar, J., Rueff, J., Gonçalves, C., Barbot, J.
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496188/
https://ncbi.nlm.nih.gov/pubmed/21039995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2010.00706.x
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