Beyond Piperacillin-Tazobactam: Cefepime and AAI101 as a Potent β-Lactam−β-Lactamase Inhibitor Combination

Impeding, as well as reducing, the burden of antimicrobial resistance in Gram-negative pathogens is an urgent public health endeavor. Our current antibiotic armamentarium is dwindling, while major resistance determinants (e.g., extended-spectrum β-lactamases [ESBLs]) continue to evolve and dissemina...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Papp-Wallace, Krisztina M., Bethel, Christopher R., Caillon, Jocelyne, Barnes, Melissa D., Potel, Gilles, Bajaksouzian, Saralee, Rutter, Joseph D., Reghal, Amokrane, Shapiro, Stuart, Taracila, Magdalena A., Jacobs, Michael R., Bonomo, Robert A., Jacqueline, Cédric
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2019
Ábhair:
Experimental Therapeutics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496078/
https://ncbi.nlm.nih.gov/pubmed/30858223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00105-19
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