Evaluation of Saliva as a Potential Alternative Sampling Matrix for Therapeutic Drug Monitoring of Levofloxacin in Patients with Multidrug-Resistant Tuberculosis

Saliva may be a useful alternative matrix for monitoring levofloxacin concentrations in multidrug-resistant tuberculosis (MDR-TB) patients. The objectives of this study were (i) to evaluate the correlation between plasma and salivary levofloxacin (Lfx) concentrations in MDR-TB patients and (ii) to g...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Ghimire, Samiksha, Maharjan, Bhagwan, Jongedijk, Erwin M., Kosterink, Jos G. W., Ghimire, Gokarna R., Touw, Daan J., van der Werf, Tjip S., Shrestha, Bhabana, Alffenaar, Jan-Willem C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496077/
https://ncbi.nlm.nih.gov/pubmed/30782999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02379-18
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