Sox2 targets cyclinE, p27 and survivin to regulate androgen‐independent human prostate cancer cell proliferation and apoptosis

OBJECTIVES: Sox2 is a major transcription factor and the transforming growth factor‐α (TGF‐α)/EGFR autocrine loop is a hallmark of prostate cancer progression. In this study, we have evaluated the effects and potential mechanisms of Sox2 on cell proliferation and apoptosis, and investigated effects...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Lin, F., Lin, P., Zhao, D., Chen, Y., Xiao, L., Qin, W., Li, D., Chen, H., Zhao, B., Zou, H., Zheng, X., Yu, X.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495851/
https://ncbi.nlm.nih.gov/pubmed/22469032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2012.00812.x
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