Heterogeneity in nuclear transport does not affect the timing of DNA synthesis in quiescent mammalian nuclei induced to replicate in Xenopus egg extracts

Intact G(0) nuclei from quiescent mammalian cells initiate DNA synthesis asynchronously in Xenopus egg extracts, despite exposure to the same concentration of replication factors. This indicates that individual nuclei differ in their ability to respond to the inducers of DNA replication. Since the i...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Sun, W.‐H., Hola, M., Baldwin, N., Pedley, K., Brooks, R.F.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Ltd 2001
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495702/
https://ncbi.nlm.nih.gov/pubmed/11284919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2001.00196.x
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